Department of Physiology and Pharmacology
WVU School of Medicine Names the 2013 Dean's Award Recipients.
•Timothy R. Nurkiewicz, Ph.D. recently received the Dean's Excellence Award in Research. Dr. Nurkiewicz's research interests are mechanisms of microvascular dysfunction due to pulmonary exposure to particles and nanoparticles.
•Mohammed A. Nayeem, MSc, PhD. was recently awarded a R01-NIH grant by the National Heart, Lung and Blood Institute /NIH to investigate the cause and effect of endothelial dysfunction which is associated with corresponding changes in vascular tone and increases in contractility, a condition that may cause hypertension in susceptible individuals with allelic variants in cyp2j-epoxygenases, soluble epoxide hydrolase and adenosine receptors. These allelic variants in humans may have similarities to our transgenic mice that regulate vascular tone and blood pressure. The outcome from this proposed study may provide us possible new targets or combination of targets for the prevention as well as for the treatment of growing number of high blood pressure individuals in this country and the world.
•Valerie Minarchick won an award for Outstanding Poster Presentation at The Cardiovascular Forum for Promoting Centers of Excellence and Young Investigators that was held at the University of Louisville, Louisville KY August 15-17. The award was sponsored by the International Academy of Cardiovascular Sciences.
•Pingian He Ph.D. was recently awarded a NIH grant by National Institute of Diabetes and Digestive and Kidney Diseases to investigate the roles of circulating microparticles, the small vesicles released from the cell surface upon activation, in the development of diabetes-associated microvascular complications. The proposed research involves both animal studies and diabetic patient blood sample analysis. The knowledge gained from the proposed studies will provide new insight into the pathogenesis of diabetes-associated vascular dysfunction and evaluate the potential of using microparticles as biomarkers to predict the risk or severity of vascular complications, as well as the efficacy of diabetic therapies.
•Stan Hileman Ph.D. was recently awarded a grant from the United States Department of Agriculture to investigate the role of three neuropeptides (kisspeptin, neurokinin B, dynorphin) in regulating the timing of puberty. The work will use female sheep to examine the actions and interaction of these neuropeptides in controlling the hypothalamic release of gonadotropin releasing-hormone, a peptide that is critical for controlling puberty onset in mammalian species. Robert Goodman Ph.D is co-investigator.
•E.J. Van Liere Professor and Chair David Siderovski, Ph.D., will begin a five-year stint as an Editorial Board member of "The Journal of Biological Chemistry." Candidates for editorial board membership undergo a rigorous selection process and typically are experienced scientists with distinguished research records. In 2004, Dr. Siderovski was awarded the John Jacob Abel Award from the American Society for Pharmacology and Experimental Therapeutics for his contributions to the discipline of molecular pharmacology.
•Julie Brefczynski-Lewis, Ph.D. received a seed 1440 Award from the Mind and Life Institute to have a Smartphone app created (by Phinney Tech, Inc., Seatle, WA) to deliver training in compassion and relaxation exercises to deal with everyday stressors.
•Karen Woodfork, Ph.D. earned a grant for innovative educational project. Norman Ferrari, M.D., vice dean for education and academic affairs, said. Karen won for her project, "Creation of Targeted Video Clips to Teach Key Concepts in the MSI & MSII Curriculum."