A headshot photo of HanTing Zhang.

HanTing Zhang, MD, PhD

Associate Professor and Researcher

Contact Information

Email
Phone
304-293-1488
Address
PO Box 9104
64 Medical Center Drive
4017/4041 HSC
Morgantown, WV 26506

Affiliations

  • Department of Behavioral Medicine & Psychiatry
  • Department of Neuroscience
  • Rockefeller Neurosciences Institute

Graduate Training

  • BS, MD, Han-Ting Zhang, MD, PhD 304-293-1488 hzhang@hsc.wvu.edu Affiliations Behavioral Medicine & Psychiatry; Physiology, Pharmacology, & Neuroscience; Blanchette Rockefeller Neurosciences Institute Graduate Training Bejing Institute of Pharmacology & Toxicology, Beijing,China; Southern Medical University (the former First Military Medical University), Guangzhou, China
  • MS, PhD, Beijing Institute of Pharmacology and Toxicology, the Academy of Military Medical Sciences, China

Fellowship

  • Pharmacology, Louisiana State University Health Sciences Center
  • Pharmacology, University of Tennessee Health Science Center

Research Interests

My major research interests focus on behavioral and cellular signaling mechanisms in treatment of neurodegenerative and neuropsychiatric disorders.Specifically, I am interested in exploring the roles of cyclic nucleotide (cAMP/cGMP) signaling in the mediation of depression, anxiety, alcohol dependence, drug abuse, and memory loss associated with neurodegenerative disorders such as Alzheimer’s disease. Techniques include various animal behavioral tests (e.g., radial arm-maze, water-maze, passive avoidance, and object recognition for memory; DRL schedule, forced-swim, and tail-suspension for depression; elevated-plus maze, holeboard, and light-dark transition for anxiety; alcohol drinking behavior, self-administration, and righting reflex for alcohol and/or drug dependence), small animal surgeries for brain microinfusions, enzyme assays, immunoblotting, immunohistochemistry, RNAi gene silencing (shRNAs, CRISPR-Cas9), optogenetics, etc. Our goals are to develop ideal treatments for neurodegenerative and neuropsychiatric disorders, drug abuse and dependence and elucidate the mechanisms whereby intracellular signaling mediates these disorders.

Figure 1

Recent Publications

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Lab Personnel

Xiujie Liang

Research Scholar, Graduate Student

Wangxin Zhang, MD

Visiting Professor