Department of
Neurology

Research

Current Research Trials

Title

Sponsor

Controlled Trial of 3, 4 Diaminopyridine in Lambert-Eaton Myasthenic Syndrome (LEMS) PI: Shumaila Sultan MD

Jacobus Pharmaceuticals

 

IRB: 1402212067

A Phase 3 randomized, multicenter, multinational, double-blinded study comparing the efficacy and safety of repeated biweekly infusions of neoGAA (GZ402666) and alglucosidase alfa in treatment-naïve patients with late onset Pompe disease (Protocol EFC14028) PI: Cheryl Smith MD, PhD

Sanofi-Genzyme

 

IRB: 1707650500

Neuroelectrical Stimulation in Guillian Barre Syndrome PI: Cheryl Smith MD, PhD

Investigator-initiated

 

IRB: 1703497861

A Phase 2, Multicenter, Randomized, Proof-of-Concept, Double-Blind, Placebo-Controlled, Parallel-Group Study, Including an Open-Label Period, Evaluating the Efficacy and Safety of 1 Subcutaneous Dose Regimen of Fremanezumab for the Treatment of Posttraumatic Headache (PTH): PI: Umer Najib MD

Teva Branded Pharmaceutical Products R & D

CRO: ICON

 

IRB: 1709763860

 

Determining the Optimal Treatment Strategy for Patients who have Chronic Migraine with Medication Overuse The MOTS Trial: Medication Overuse Treatment Strategy PI: David B. Watson MD/Kristina Lopez MD

Patient Centered Outcomes Research Institute (PCORI)

 

IRB: 1801958083

A RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PARALLEL, SHAM-CONTROLLED STUDY OF NON-INVASIVE VAGUS NERVE STIMULATION (nVNS) FOR THE PREVENTION OF MIGRAINES. (PREMIUM II)

PI: Umer Najib MD

electroCore

 

IRB: 1809270321

A Randomized, Double-Blind, Placebo-Controlled, Multiple Dose Study to Assess the Safety and Efficacy of Elezanumab when Added to Standard of Care in Progressive Forms of Multiple Sclerosis [Protocol M14-397]  PI: Ann Murray MD

AbbVie

 

IRB: 1811366960

A Randomized, Double-Blind, Placebo-Controlled, Multiple Dose Study to Assess the Safety and Efficacy of Elezanumab when Added to Standard of Care in Relapsing Forms of Multiple Sclerosis [Protocol M18-918]   PI: Ann Murray MD

AbbVie

 

IRB: 1811367264

Comprehensive Outcomes Registry in Subjects with Epilepsy Treated with Vagus Nerve Stimulation Therapy (Core-VNS) [Protocol No. LNN-801] PI: Zubeda Sheikh

LivaNova USA

 

Central IRB: WIRB

IRB: 1811357136