Moriah Katt, PhD

Assistant Professor, Department of Biomedical and Chemical Engineering

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Address: HSC: 108 Biomedical Drive, BMRF Room 113
Engineering: 1306 Evansdale Drive, ESB Room 513
Morgantown, WV 26506

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Recent Publications

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Pamies D, Wiersma D, Katt ME, Zhao L, Burtscher J, Harris G, Smirnova L, Searson PC, Hartung T, Hogberg HT. Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity. Neurobiol Dis. 2022 Jul;169:105719. doi: 10.1016/j.nbd.2022.105719.
Lajoie JM, Katt ME, Waters EA, Herrin BR, Shusta EV. Identification of lamprey variable lymphocyte receptors that target the brain vasculature. Sci Rep. 2022 Apr 11;12(1):6044. doi: 10.1038/s41598-022-09962-8.
Gastfriend BD, Foreman KL, Katt ME, Palecek SP, Shusta EV. Integrative analysis of the human brain mural cell transcriptome. J Cereb Blood Flow Metab. 2021 Nov;41(11):3052-3068. doi: 10.1177/0271678X211013700.
Katt ME, Shusta EV. In vitro Models of the Blood-Brain Barrier: Building in physiological complexity. Curr Opin Chem Eng. 2020 Dec;30:42-52. doi: 10.1016/j.coche.2020.07.002.
Katt ME, Mayo LN, Ellis SE, Mahairaki V, Rothstein JD, Cheng L, Searson PC. The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model. Fluids Barriers CNS. 2019 Jul 15;16(1):20. doi: 10.1186/s12987-019-0139-4.
Wong AD, Russell LM, Katt ME, Searson PC. Chemotherapeutic Drug Delivery and Quantitative Analysis of Proliferation, Apoptosis, and Migration in a Tissue-Engineered Three-Dimensional Microvessel Model of the Tumor Microenvironment. ACS Biomater Sci Eng. 2019 Feb 11;5(2):633-643. doi: 10.1021/acsbiomaterials.8b00877.
Katt ME, Linville RM, Mayo LN, Xu ZS, Searson PC. Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation. Fluids Barriers CNS. 2018 Feb 20;15(1):7. doi: 10.1186/s12987-018-0092-7.
Katt ME, Wong AD, Searson PC. Dissemination from a Solid Tumor: Examining the Multiple Parallel Pathways. Trends Cancer. 2018 Jan;4(1):20-37. doi: 10.1016/j.trecan.2017.12.002.
Katt ME, Xu ZS, Gerecht S, Searson PC. Human Brain Microvascular Endothelial Cells Derived from the BC1 iPS Cell Line Exhibit a Blood-Brain Barrier Phenotype. PLoS One. 2016;11(4):e0152105. doi: 10.1371/journal.pone.0152105.
Katt ME, Placone AL, Wong AD, Xu ZS, Searson PC. In Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right Platform. Front Bioeng Biotechnol. 2016;4:12. doi: 10.3389/fbioe.2016.00012.