A headshot photo of Vincent S. Setola.

Vincent S. Setola, PhD

Assistant Professor, PI/Director - Laboratory of Neuroscience and Genetics of Substance Abuse

Contact Information

PO Box 9303
Morgantown, WV 26506


  • Department of Neuroscience
  • Department of Behavioral Medicine & Psychiatry
  • Rockefeller Neurosciences Institute

Graduate Training

  • MSc, Université Pierre et Marie Curie (Paris VI)
  • PhD, Case Western Reserve University School of Medicine


  • Plasmalemmal monoamine transporter-G protein-coupled receptor interactions, Université Pierre et Marie Curie (Paris VI)

Research Interests

Our group is currently interested in the genetics of opioid addiction and treatment outcome. We are working with colleagues at the Chestnut Ridge Comprehensive Opioid Addiction Treatment (COAT) clinic to recruit volunteers into a genetic study of polymorphisms that predict success in the COAT paradigm. We are also working with collaborators at Marshall University to identify, via whole-exome sequencing of mother-baby dyads, susceptibility loci for neonatal abstinence syndrome. Finally, our lab has a mouse model of altered response to drugs of addiction, which we are using to better understand the brain regions and molecular players involved in the signal transduction pathways of drugs of abuse. 

Research Topics
  1. Drug abuse
  2. G protein signaling
  3. Human genetics
  4. Monoamine transporters
  5. Signal transduction
  6. Single nucleotide polymorphisms

Recent Publications