Recent Publications
Exploratory single-nucleus multiomics analysis of myeloid cell states associated with neoadjuvant chemotherapy response in pancreatic ductal adenocarcinoma.
Ojetunde M, Ma L, Goodney HG, Stevens AM, Mizener A, Pistilli EE, Ott S, Abdilleh K, Szomolay B, Hu G, Eubank TD, Boone BA. Clin Transl Med. 2026 Sep;16(9):e70810. PMID: 42735906.
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Caught in the NET: A Review on the Emerging Role of Neutrophil Extracellular Traps in PDAC Development.
Godfrey EA, Lukomski S, Boone BA. Technol Cancer Res Treat. 2026 Jan-Dec;25:15330338261470694. Epub 2026 Jul 22. PMID: 42485000.
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Physical, chemical, and structural properties of human gastric organoid-derived mucus.
Lyon KN, Sidar B, Gattiker J, Dudiak C, Vermulm C, Jordan G, Sebrell TA, Morris MT, Tabone L, Szoka N, Abunnaja S, Boone BA, Busada JT, Burcham A, Domanico L, Helm RF, Liao W, Davis B, Brown J, McCalla SG, Wilking JN, Bansil R, Bimczok D. Am J Physiol Gastrointest Liver Physiol. 2026 Aug 1;331(2):G244-G261. Epub 2026 Jul 16. PMID: 42460667.
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Impact of Surgical Approach on Post-Pancreatoduodenectomy Bleeding: A Multi-Center Analysis.
Hays SB, Kuchta K, Castillo S, Ceuppens S, Espinosa C, Mehdi SA, Nunez-Rocha RE, Ranson K, Rojas AE, Tcharni A, Tirukkovalur NV, Vallorani A, Rieser C, Boone BA, Paniccia A, Polanco PM, Schmidt CR, Talamonti MS, Zeh HJ 3rd, Zureikat AH, Hogg ME. Ann Surg. 2026 May 4. PMID: 42081086.
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Thromboelastography Characterizes the Hypercoagulable State in Murine and Human Breast Cancer. Clin Breast Cancer.
Niemann B, Harvey W, Ranson K, Espinosa C, Hoblitzell HE, Rao P, Lupinacci K, Bailey K, Hazard-Jenkins H, Partin J, Eubank TD, Boone BA. 2026 May;26(5):154-161.e1. Epub 2026 Apr 1. PMID: 42034541.
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Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib.
Niemann B, Puleo A, Sestito MP, Schmidt CR, Boone BA.J Vis Exp. 2026 Apr 3;(230). PMID: 42008356.
DNA/RNA-Based Next-Generation Sequencing Improves the Early Diagnosis and Management of Neoplastic Bile Duct Strictures: A 6-Year, Prospective, Multi-Institutional, Real-Time Study.
Das R, Kleinberger J, Sawas T, Wald AI, Bubar R, Singh H, Chennat J, Khalid A, Romutis SL, Rabinovitz M, Tavakkoli A, Fairley KJ, Boone BA, Sarkaria S, Nasr J, Thiruvengadam NR, Gabbert C, Mahmood S, Messallam AA, Gjeorgjievski M, Goldschmiedt M, Thakkar S, Tielleman T, Dugum M, Reich J, Singh S, Brand RE, McGrath K, Fasanella K, Lennon AM, Reddy R, Shrestha R, Ellis DJ, Singhi SA, Lee T, Kay PS, Lee RD, Chua TY, Nassour I, Buxbaum JL, Law JK, Bhat Y, Jamidar PA, Jonica ER, Easler JJ, Skef W, Vanderveldt HD, Dasyam AK, Geller DA, Zureikat AH, Zeh HJ, Polanco PM, Marsh JW, Hogg M, Lee KK, Pingpank JF, Choudry MHA, Humar A, Schmidt C, Mansour J, Nunns G, Ongchin M, Paniccia A, Lajara S, Monaco SE, Ohori NP, Pantanowitz L, Mitchell JM, Smith K, Shaker N, Singhi AH, Hsu D, Saeed A, Sahin IH, Zhang J, Gorantla V, Rhee J, Nikiforova MN, Kubiliun N, Slivka A, Singhi AD. Gastroenterology. 2026 Aug;171(2):325-341. Epub 2026 Mar 27. PMID: 41905432.
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Application of group A streptococcal collagen-like protein 1-expressing Lactococcus as a novel immunotherapeutic against pancreatic ductal adenocarcinoma.
Godfrey EA, Choi SJ, Sestito M, Liu TW, Lukomski S, Boone BA. Sci Rep. 2026 Jan 21;16(1):5911. PMID: 41565749.
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Intraoperative Video Consultation Following Bile Duct Transection Facilitates Direct OR Transfer for Robotic Hepaticojejunostomy at Tertiary Center.
Sestito MP, Stevens AM, Niemann B, Boone BA. J Vis Exp. 2026 Jan 9;(227). PMID: 41587153.
Pretreatment CA19-9 Predicts Survival in Pancreatic Cancer With Optimal Response to Neoadjuvant Therapy.
Gebran A, Chopra A, Farah E, Hays S, Ranson K, Rojas A, Ceuppens S, Schmitz R, Liu H, Tirukkovalur NV, Talamonti M, Lee KK, Zeh HJ, Schmidt C, Boone BA, Hogg M, Zureikat AH, Polanco PM, Paniccia A. J Surg Oncol. 2026 Feb;133(2):177-185. Epub 2025 Dec 31. PMID: 41474314.
Imaging Reactive Oxygen Species with L-012 Reveals Neutrophil Extracellular Trap Formation in Pancreatic Ductal Adenocarcinoma.
Basnet A, Landreth KM, Sestito M, Ranson K, Gammon ST, Piwnica-Worms D, Boone BA, Liu TW. Antioxidants (Basel). 2025 Dec 8;14(12):1473. PMID: 41462673.
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Neutrophil extracellular trap inhibition revitalizes PDAC immunotherapy responsiveness via reduced fibrosis and TCF1+CD8+progenitor T-cell expansion.
Niemann B, Ivey A, Hopen Q, Dakhlallah D, Brundage K, Mihalik N, Eubank T, Boone BA. Oncoimmunology. 2025 Dec;14(1):2601394. Epub 2025 Dec 18. PMID: 41411661.
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PancreaSeq Genomic Classifier (PancreaSeq GC) Improves Pancreatic Cyst Classification and Detection of Advanced Neoplasia: A Multi-institutional Validation Study.
Singhi AD, Wald AI, Smith K, Wolkenstein L, Bubar RD, Diaz-Aragon R, Grupillo M, Guckin D, Lai YT, Brand RE, McGrath K, Park WG, Pfau PR, Polanco PM, Kubiliun N, DeWitt J, Easler JJ, Dam A, Mok SR, Wallace MB, Boone BA, Marsh W, Thakkar S, Fairley KJ, Afghani E, Bhat Y, Ramrakhiani S, Nasr J, Thiruvengadam NR, Khalid A, Fasanella K, Chennat J, Das R, Singh H, Slivka A, Gabbert C, Sawas T, Tielleman T, Vanderveldt HD, Tavakkoli A, Smith LM, Singhi AH, Singhi SA, Romutis S, Mahmood S, Hosmer AE, McNabb-Baltar J, Lennon AM, Hruban RH, Shaker N, Paniccia A, Zureikat A, Lee KK, Ongchin M, Zeh H, Minter R, Schmidt CM, He J, Nikiforova MN. Ann Surg Oncol. 2026 Apr;33(4):2865-2875. Epub 2025 Dec 12. PMID: 41388172.
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Reconfigurable animal bed-EPR resonator assembly for multimodal co-registration.
Tseytlin O, Sestito M, Eubank TD, Khramtsov VV, Driesschaert B, Boone BA, Tseytlin M. J Magn Reson. 2026 Jan;382:107995. Epub 2025 Nov 26. PMID: 41319401.
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Robotic-assisted Lateral Pancreaticojejunostomy for Chronic Pancreatitis.
Sestito MP, Schwartzman KH, Niemann B, Schmidt CR, Boone BA. J Vis Exp. 2025 Sep 5;(223). PMID: 40982384.
Does a robotic approach decrease morbidity and mortality following pancreaticoduodenectomy for octogenarians? An American multi-center analysis.
Hays SB, Kuchta K, Abreu AA, Chopra A, Farah E, Kannan A, Mehdi SA, Radi I, Ranson K, Rojas AE, Tcharni A, Boone BA, Paniccia A, Polanco PM, Schmidt CR, Talamonti MS, Zeh HJ, Zureikat AH, Hogg ME. HPB (Oxford). 2025 Nov;27(11):1400-1409. Epub 2025 Jul 30. PMID: 40813199.
Hydroxychloroquine reduces metastatic tumor burden in pancreatic adenocarcinoma through myeloperoxidase inhibition.
Niemann B, Rao P, Hopen Q, Landreth K, Basnet A, Geldenhuys W, Liu TW, Boone BA. J Inflamm (Lond). 2025 Aug 12;22(1):33. doi: 10.1186/s12950-025-00456-8. PMID: 40797324.
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Neutrophil Extracellular Traps Modulate Recruitment and Immunosuppression of Macrophages in Pancreatic Adenocarcinoma.
Pratt HG, Stevens AM, Sestito M, Ojetunde M, Ivey AD, Mihalik NE, Steinberger KJ, Niemann B, Hoblitzell EH, Wan E, Eubank TD, Boone BA. Cancer Immunol Res. 2025 Oct 1;13(10):1547-1560. PMID: 40742388.
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Multimodal Therapy May be Key to Improving Survival for Octogenarians Undergoing Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma: An American Multicenter Analysis.Hays SB, Kuchta K, Abreu AA, Chopra A, Farah E, Kannan A, Mehdi SA, Radi I, Ranson K, Rieser C, Rojas AE, Tcharni A, Boone BA, Paniccia A, Polanco PM, Schmidt CR, Talamonti MS, Zeh HJ 3rd, Zureikat AH, Hogg ME. Ann Surg Oncol. 2025 May;32(5):3582-3592. Epub 2025 Jan 27. PMID: 39871074.
Rare triad of anomalous biliary anatomy (pancreaticobiliary maljunction), choledochal cyst and cholangiocarcinoma in a 45-year-old white male: A case report.
Markovich B, Lombard C, Boone BA, Thakkar S, Puleo NA, Ali S. Radiol Case Rep. 2024 Oct 26;20(1):304-309. PMID: 39539383.
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Unraveling the gut microbiome's contribution to pancreatic ductal adenocarcinoma: mechanistic insights and therapeutic perspectives.
Tabrizi E, Pourteymour Fard Tabrizi F, Mahmoud Khaled G, Sestito MP, Jamie S, Boone BA. Front Immunol. 2024 Jul 9;15:1434771. PMID: 39044834.
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Employing Advanced Technology to Reduce Postoperative Pancreatic Fistula.
Boone BA. Ann Surg Open. 2024 Jan 9;5(1):e373. PMID: 38883937.
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Implementing a Robotic Hepatopancreatobiliary Program for New Faculty: Safety, Feasibility and Lessons Learned.
Niemann B, Kenney C, Wallis Marsh J, Schmidt C, Boone BA. Res Sq [Preprint]. 2024 Apr 24:rs.3.rs-4271384. doi: 10.21203/rs.3.rs-4271384/v1. Update in: J Robot Surg. 2024 Jun 15;18(1):253. PMID: 38746355.
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A streptococcal collagen-like protein 1 restricts tumor growth in murine pancreatic adenocarcinoma and inhibits cancer-promoting neutrophil extracellular traps.
Henderson EA, Ivey A, Choi SJ, Santiago S, McNitt D, Liu TW, Lukomski S, Boone BA. Group Front Immunol. 2024 Mar 7;15:1363962. PMID: 38515758.
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Analysis of single nuclear chromatin accessibility reveals unique myeloid populations in human pancreatic ductal adenocarcinoma.
Pratt HG, Ma L, Dziadowicz SA, Ott S, Whalley T, Szomolay B, Eubank TD, Hu G, Boone BA. Clin Transl Med. 2024 Mar;14(3):e1595. PMID: 38426634.
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Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer.
Basnet A, Landreth KM, Nohoesu R, Santiago SP, Geldenhuys WJ, Boone BA, Liu TW. Cancer Immunol Immunother. 2024 Feb 17;73(3):57. PMID: 38367056.
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Prophylactic Hyperthermic Intraperitoneal Chemotherapy for Patients at High Risk of Developing Gallbladder Cancer Peritoneal Metastases: Case Report and Rationale for a Prospective Clinical Trial.
Crum AE, Sestito M, Garland-Kledzik M, Boone BA. J Clin Med. 2024 Jan 29;13(3):768. PMID: 38337462.
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Pancreatectomy Induces Cancer-Promoting Neutrophil Extracellular Traps.
Ivey AD, Pratt HG, Niemann B, Ranson K, Puleo A, Fagan BM, Rao P, Landreth KM, Liu TW, Boone BA. Ann Surg Oncol. 2024 Jun;31(6):3707-3717. Epub 2024 Jan 18. PMID: 38238536.
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Emerging applications of cancer bacteriotherapy towards treatment of pancreatic cancer.
Henderson EA, Lukomski S, Boone BA. Front Oncol. 2023 Jul 19;13:1217095. PMID: 37588093.
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Robotic modified Strong procedure for superior mesenteric artery syndrome.
Wasef K, Hudnall A, Schmidt CR, Marsh JW, Boone BA. Clin Case Rep. 2023 Jul 17;11(7):e7651. PMID: 37465243.
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A Combined DNA/RNA-based Next-Generation Sequencing Platform to Improve the Classification of Pancreatic Cysts and Early Detection of Pancreatic Cancer Arising From Pancreatic Cysts.
Nikiforova MN, Wald AI, Spagnolo DM, Melan MA, Grupillo M, Lai YT, Brand RE, O'Broin-Lennon AM, McGrath K, Park WG, Pfau PR, Polanco PM, Kubiliun N, DeWitt J, Easler JJ, Dam A, Mok SR, Wallace MB, Kumbhari V, Boone BA, Marsh W, Thakkar S, Fairley KJ, Afghani E, Bhat Y, Ramrakhiani S, Nasr J, Skef W, Thiruvengadam NR, Khalid A, Fasanella K, Chennat J, Das R, Singh H, Sarkaria S, Slivka A, Gabbert C, Sawas T, Tielleman T, Vanderveldt HD, Tavakkoli A, Smith LM, Smith K, Bell PD, Hruban RH, Paniccia A, Zureikat A, Lee KK, Ongchin M, Zeh H, Minter R, He J, Nikiforov YE, Singhi AD. Ann Surg. 2023 Oct 1;278(4):e789-e797. Epub 2023 May 22. PMID: 37212422.
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Chloroquine reduces neutrophil extracellular trap (NET) formation through inhibition of peptidyl arginine deiminase 4 (PAD4).
Ivey AD, Matthew Fagan B, Murthy P, Lotze MT, Zeh HJ, Hazlehurst LA, Geldenhuys WJ, Boone BA. Clin Exp Immunol. 2023 Mar 24;211(3):239-247. PMID: 36655514.
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Acute pancreatitis induces a transient hypercoagulable state in murine models.
Rao P, Niemann B, Szeligo B, Ivey AD, Murthy P, Schmidt CR, Boone BA. Pancreatology. 2023 Apr;23(3):306-313. Epub 2023 Mar 3. PMID: 36898897.
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Biologic Functions of Hydroxychloroquine in Disease: From COVID-19 to Cancer.
Niemann B, Puleo A, Stout C, Markel J, Boone BA. Pharmaceutics. 2022 Nov 22;14(12):2551. PMID: 36559044.
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Defining the Optimal Duration of Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma: Time for a Personalized Approach?
Puleo A, Malla M, Boone BA. Pancreas. 2022 Oct 1;51(9):1083-1091. PMID: 37078929.
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Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts.
Paniccia A, Polanco PM, Boone BA, Wald AI, McGrath K, Brand RE, Khalid A, Kubiliun N, O'Broin-Lennon AM, Park WG, Klapman J, Tharian B, Inamdar S, Fasanella K, Nasr J, Chennat J, Das R, DeWitt J, Easler JJ, Bick B, Singh H, Fairley KJ, Sarkaria S, Sawas T, Skef W, Slivka A, Tavakkoli A, Thakkar S, Kim V, Vanderveldt HD, Richardson A, Wallace MB, Brahmbhatt B, Engels M, Gabbert C, Dugum M, El-Dika S, Bhat Y, Ramrakhiani S, Bakis G, Rolshud D, Millspaugh G, Tielleman T, Schmidt C, Mansour J, Marsh W, Ongchin M, Centeno B, Monaco SE, Ohori NP, Lajara S, Thompson ED, Hruban RH, Bell PD, Smith K, Permuth JB, Vandenbussche C, Ernst W, Grupillo M, Kaya C, Hogg M, He J, Wolfgang CL, Lee KK, Zeh H, Zureikat A, Nikiforova MN, Singhi AD. Gastroenterology. 2023 Jan;164(1):117-133.e7. Epub 2022 Oct 6. PMID: 36209796.
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Molecular pathogenesis and emerging targets of gastric adenocarcinoma.
Ivey A, Pratt H, Boone BA. J Surg Oncol. 2022 Jun;125(7):1079-1095. PMID: 35481910.
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Macrophage and Neutrophil Interactions in the Pancreatic Tumor Microenvironment Drive the Pathogenesis of Pancreatic Cancer.
Pratt HG, Steinberger KJ, Mihalik NE, Ott S, Whalley T, Szomolay B, Boone BA, Eubank TD. Cancers (Basel). 2021 Dec 31;14(1):194. PMID: 35008355.
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Quantifying Performance in Robotic Surgery Training Using Muscle-Based Activity Metrics.
Gritsenko V, Moon T, Boone BA, Yakovenko S. IEEE Int Conf Syst Eng Technol. 2021 Nov;2021:358-362. Epub 2021 Nov 30. PMID: 37228383.
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Encouraging long-term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high-risk patients with resectable pancreatic carcinoma.
AlMasri SS, Zenati MS, Desilva A, Nassour I, Boone BA, Singhi AD, Bartlett DL, Liotta LA, Espina V, Loughran P, Lotze MT, Paniccia A, Zeh HJ 3rd, Zureikat AH, Bahary N. Cancer Med. 2021 Oct;10(20):7233-7241. Epub 2021 Sep 24. PMID: 34559451.
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Poor Response to Checkpoint Immunotherapy in Uveal Melanoma Highlights the Persistent Need for Innovative Regional Therapy Approaches to Manage Liver Metastases.
Szeligo BM, Ivey AD, Boone BA. Cancers (Basel). 2021 Jul 8;13(14):3426. PMID: 34298647.
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Development of a Senior Medical Student Robotic Surgery Training Elective.
Mullens CL, Van Horn AL, Marsh JW, Hogg ME, Thomay AA, Schmidt CR, Boone BA. J Med Educ Curric Dev. 2021 Jun 29;8:23821205211024074. PMID: 34263057.
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Immune Cell Modulation of the Extracellular Matrix Contributes to the Pathogenesis of Pancreatic Cancer.
Ahmad RS, Eubank TD, Lukomski S, Boone BA. Biomolecules. 2021 Jun 17;11(6):901. PMID: 34204306.
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SMAD4 loss is associated with response to neoadjuvant chemotherapy plus hydroxychloroquine in patients with pancreatic adenocarcinoma.
Fei N, Wen S, Ramanathan R, Hogg ME, Zureikat AH, Lotze MT, Bahary N, Singhi AD, Zeh HJ, Boone BA. Clin Transl Sci. 2021 Sep;14(5):1822-1829. Epub 2021 May 18. PMID: 34002944.
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Baseline Plasma Inflammatory Profile Is Associated With Response to Neoadjuvant Chemotherapy in Patients With Pancreatic Adenocarcinoma.
Chopra A, Zamora R, Vodovotz Y, Hodges JC, Barclay D, Brand R, Simmons RL, Lee KK, Paniccia A, Murthy P, Lotze MT, Boone BA, Zureikat AH. J Immunother. 2021 Jun 1;44(5):185-192. PMID: 33935273.
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Impact of postoperative pancreatic fistula on long-term oncologic outcomes after pancreatic resection.
Bonaroti JW, Zenati MS, Al-Abbas AI, Rieser CJ, Zureikat AH, Hogg ME, Zeh HJ, Boone BA. HPB (Oxford). 2021 Aug;23(8):1269-1276. Epub 2021 Jan 16. PMID: 33526357.
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Tumor Size Differences Between Preoperative Endoscopic Ultrasound and Postoperative Pathology for Neoadjuvant-Treated Pancreatic Ductal Adenocarcinoma Predict Patient Outcome.
Das R, McGrath K, Seiser N, Smith K, Uttam S, Brand RE, Fasanella KE, Khalid A, Chennat JS, Sarkaria S, Singh H, Slivka A, Zeh HJ, Zureikat AH, Hogg ME, Lee KK, Paniccia A, Ongchin MC, Pingpank JF, Boone BA, Dasyam AK, Bahary N, Gorantla VC, Rhee JC, Thomas R, Ellsworth S, Landau MS, Ohori NP, Henn P, Shyu S, Theisen BK, Singhi AD. Clin Gastroenterol Hepatol. 2022 Apr;20(4):886-897. Epub 2020 Dec 3. PMID: 33278573.
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Outcomes of Neoadjuvant Chemotherapy Versus Chemoradiation in Localized Pancreatic Cancer: A Case-Control Matched Analysis.
Chopra A, Hodges JC, Olson A, Burton S, Ellsworth SG, Bahary N, Singhi AD, Boone BA, Beane JD, Bartlett D, Lee KK, Hogg ME, Lotze MT, Paniccia A, Zeh H, Zureikat AH. Ann Surg Oncol. 2021 Jul;28(7):3779-3788. Epub 2020 Nov 24. PMID: 33231769.
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Formal robotic training diminishes the learning curve for robotic pancreatoduodenectomy: Implications for new programs in complex robotic surgery.
Schmidt CR, Harris BR, Musgrove KA, Rao P, Marsh JW, Thomay AA, Hogg ME, Zeh HJ, Zureikat AH, Boone BA. J Surg Oncol. 2021 Feb;123(2):375-380. Epub 2020 Nov 2. PMID: 33135785.
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Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients.
Zeh HJ, Bahary N, Boone BA, Singhi AD, Miller-Ocuin JL, Normolle DP, Zureikat AH, Hogg ME, Bartlett DL, Lee KK, Tsung A, Marsh JW, Murthy P, Tang D, Seiser N, Amaravadi RK, Espina V, Liotta L, Lotze MT. Clin Cancer Res. 2020 Jul 1;26(13):3126-3134. PMID: 32156749.
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Neutrophil extracellular traps in breast cancer and beyond: current perspectives on NET stimuli, thrombosis and metastasis, and clinical utility for diagnosis and treatment.
Snoderly HT, Boone BA, Bennewitz MF. Breast Cancer Res. 2019 Dec 18;21(1):145. PMID: 31852512.
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500 Minimally Invasive Robotic Pancreatoduodenectomies: One Decade of Optimizing Performance.
Zureikat AH, Beane JD, Zenati MS, Al Abbas AI, Boone BA, Moser AJ, Bartlett DL, Hogg ME, Zeh HJ 3rd. Ann Surg. 2019 Dec 5. PMID: 31851003.
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Prognostic Value of the Systemic Immune-Inflammation Index (SII) After Neoadjuvant Therapy for Patients with Resected Pancreatic Cancer.
Murthy P, Zenati MS, Al Abbas AI, Rieser CJ, Bahary N, Lotze MT, Zeh HJ 3rd, Zureikat AH, Boone BA. Ann Surg Oncol. 2020 Mar;27(3):898-906. PMID: 31792715.
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DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth.
Miller-Ocuin JL, Liang X, Boone BA, Doerfler WR, Singhi AD, Tang D, Kang R, Lotze MT, Zeh HJ 3rd. Oncoimmunology. 2019 Jun 11;8(9):e1605822. PMID: 31428515.
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Neoadjuvant FOLFIRINOX in Patients With Borderline Resectable Pancreatic Cancer: A Systematic Review and Patient-Level Meta-Analysis.
Janssen QP, Buettner S, Suker M, Beumer BR, Addeo P, Bachellier P, Bahary N, Bekaii-Saab T, Bali MA, Besselink MG, Boone BA, Chau I, Clarke S, Dillhoff M, El-Rayes BF, Frakes JM, Grose D, Hosein PJ, Jamieson NB, Javed AA, Khan K, Kim KP, Kim SC, Kim SS, Ko AH, Lacy J, Margonis GA, McCarter MD, McKay CJ, Mellon EA, Moorcraft SY, Okada KI, Paniccia A, Parikh PJ, Peters NA, Rabl H, Samra J, Tinchon C, van Tienhoven G, van Veldhuisen E, Wang-Gillam A, Weiss MJ, Wilmink JW, Yamaue H, Homs MYV, van Eijck CHJ, Katz MHG, Groot Koerkamp B. J Natl Cancer Inst. 2019 Aug 1;111(8):782-794. PMID: 31086963.
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The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth.
Boone BA, Murthy P, Miller-Ocuin JL, Liang X, Russell KL, Loughran P, Gawaz M, Lotze MT, Zeh HJ 3rd, Vogel S, et al. Ann Hematol. 2019 Jul;98(7):1603-1610. PMID: 31020347.
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Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine.
Murthy P, Singhi AD, Ross MA, Loughran P, Paragomi P, Papachristou GI, Whitcomb DC, Zureikat AH, Lotze MT, Zeh Iii HJ, Boone BA. Front Immunol. 2019 Jan 24;10:28. PMID: 30733719.
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Risk of Venous Thromboembolism for Patients with Pancreatic Ductal Adenocarcinoma Undergoing Preoperative Chemotherapy Followed by Surgical Resection.
Boone BA, Zenati MS, Rieser C, Hamad A, Al-Abbas A, Zureikat AH, Hogg ME, Neal MD, Zeh HJ 3rd. Ann Surg Oncol. 2019 May;26(5):1503-1511. Epub 2019 Jan 16. PMID: 30652227.
Can post-hoc video review of robotic pancreaticoduodenectomy predict portal/superior mesenteric vein margin status in pancreatic adenocarcinoma?
Jung JP, Zenati MS, Hamad A, Hogg ME, Simmons RL, Zureikat AH, Zeh HJ, Boone BA. HPB (Oxford). 2019 Jun;21(6):679-686. Epub 2018 Nov 28. PMID: 30501987.
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Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps.
Boone BA, Murthy P, Miller-Ocuin J, Doerfler WR, Ellis JT, Liang X, Ross MA, Wallace CT, Sperry JL, Lotze MT, Neal MD, Zeh HJ 3rd. BMC Cancer. 2018 Jun 22;18(1):678. PMID: 29929491.
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