Department of
Orthopaedics

Research

The Adult Reconstruction Service participates in the American Joint Replacement Registry (AJRR) and has an electronic patient database for clinical and translational research.  The fellow has access the Musculoskeletal Research Laboratory for work on prosthetic joint infection and biofilm, biomechanics, cell therapies, and nanotechnologies.  The fellow is expected to produce high quality research for publication and presentation at meetings and at least a half-day a week will be dedicated to research.  The laboratory staff includes PhD faculty, research specialists, coordinators and assistants to assist with projects.  The laboratory coordinates multidisciplinary research with the Departments of Microbiology & Immunology, Pathology, and Infectious Diseases and promotes collaboration with the West Virginia University College of Engineering.

  1. Li B, Jiang B, Dietz MJ, Smith ES, Clovis NB, Rao M. Evaluation of Local MCP-1 and IL-12 Nanocoatings for Infection Prevention in Open Fractures. J Orthop Res. 2010 Jan; 28(1):48-54. PMID: 19588527.
  1. Shuler, FD, Dietz MJ. Physician's Ability to Manually Detect Elevations in Intra-Compartmental Pressures. J Bone Joint Surg – Am. 2010 Feb; 92: 361-367. PMID: 20124063.
  1. Dietz MJ, Lavender C, Emery SE, Clovis N, Shuler FD, Zuberi, J. ATV-Related Orthopaedic Trauma in North Central West Virginia: An 8-Year Review of a Level I Trauma Center. J Orthop Trauma. 2012; 26(7): e83-7. PMID: 22337482.
  1. Hamza T, Dietz M, Pham D, Clovis N, Danley S, Li B. Intra-cellular Staphylococcus aureus Alone Causes Infection In Vivo. Eur Cell Mater. 2013; 25: 341-50. Kuching, Malaysia. August 2013. PMID: 23832687. Asia Pacific Orthopaedic Association (APOA)-Pfizer Best Scientific Paper Award.
  1. Dietz MJ, Chase S, Burke D, Kwon YM. Novel Technique for Removal of a Broken Intracortical Screw During Total Hip Arthroplasty. Orthopedics. 2013; 36(9): 846-9. PMID: 24200426.
  1. Dietz MJ, Choi H, Freiberg A, Bedair H. Transfer of Patient Care Between Stages of a Two-Stage Exchange for Chronic Periprosthetic Joint Infection Leads to Inferior Outcomes. J of Arthroplasty. 2014; 29 (7): 1426-9. PMID: 24581900.
  1. Bedair H, Goyal N, Dietz MJ, Urish K, Hansen V, Manrique J, Zmistowski B, Tokarski A, Restrepo C, Deirmengian G. A History of Treated Periprosthetic Joint Infection Increases the Risk of Subsequent Different Site Infection. Clin Orthop Relat Res. 2015 Jul;473(7):2300-4. PMID: 25670654.
  1. Dietz MJ, Springer BD, Barnes PD, Falcigilia MM, Friedrich AD, Berendt AR, Calhoun JH, Manner PA. Best Practices for Centers of Excellence in Addressing Periprosthetic Joint Infection. A Synopsis of the AAOS Musculoskeletal Infection: Where Are We in 2014? J of Amer Assoc Ortho Surg. 2015 March Suppl 1. PMID: 25808965.
  1. Tidwell JE, Dawson-Andoh B, Adedipe EO, Nkansah K, Dietz MJ. Characterization of Implant Associated Biofilm with Near Infrared Spectroscopy. Clin Orthop Relat Res. 2015 Nov; 473(11): 3638-46. PMID: 26265208.
  1. Hanselman A, Montague M, Murphy TR, Dietz MJ. Contamination Relative to the Activation Timing of Filtered-Exhaust Helmets. J of Arthroplasty. 2016 Apr;31(4):776-80. PMID: 26684270.
  1. DiBlasi JF, Smith RP, Garavaglia J, Quedado J, Frye BM, Dietz MJ. Comparing Cost and Efficacy of Intravenous versus Topical Tranexamic Acid in Total Hip and Knee Arthroplasty. Am J Orthopedics. 2016 November/December: E439-E443. PMID: 28005108.
  1. Dietz MJ, Sprando D, Hanselman A, Regier M, Frye BM. Smartphone Assessment of Knee Flexion Compared to Radiographic Standards. The Knee. 2017 March; 24(2): 224-230. PMID: 28179062.
  1. Joseph EG, Ernest EP, Dietz MJ. Complicated Total Knee Arthroplasty in Klippel-Trenaunay-Weber Syndrome. JBJS Case Connector. 2017 Jul-Sep; 7(3): e73. doi: 10.2106/JBJS.CC.15.00256. PMID: 29244707.
  1. Grisez BT, Calkins TE, Dietz MJ. Modular Femoral Stems in Revision Total Hip Arthroplasty. Operative Techniques in Orthopaedics. 2017 Sep: 27(3): 178-185. DOI: 10.1053/j.oto.2017.05.006
  1. Lastinger A, Dietz MJ, Guilfoose J, Sarwari AR. Clinical Experience with Tigecycline in the Treatment of Prosthetic Joint Infection. Open Forum Infectious Diseases. 2017 Oct; (Suppl_1): S98. PMCID: PMC5631670.
  1. Ernest EP, Machi AS, Karolcik BA, Dietz MJ. Topical Adjuvants Incompletely Remove Adherent Staphylococcus aureus from implant materials. J Orthop Res. 2018 Jun;36(6):1599-1604. doi: 10.1002/jor.23804. PMID: 29139579.
  1. Allison JE, Lastinger AM, Guilfoose JA, Dietz MJ. Suppressive Oral Antibiotics in Orthopaedic Prosthetic Joint Infections. West Virginia Medical Journal –OA. 2018 Jan (1-7); doi: 21885/wvmj.2018.1.
  1. Dietz MJ. CORR Insights: The John N. Insall Award Higher Tissue Concentrations of Vancomycin Achieved with Intraosseous Regional Prophylaxis in Revision TKA. A Randomized Controlled Trial. Clin Orthop Relat Res. 2018 476: 75-76. PMID: 29529619.
  1. Dietz MJ, Hare JT, Ueno C, Prudhomme BJ, Boyd JW. Laser Assisted Fluorescent Angiography to Assess Tissue Perfusion in the Setting of Traumatic Elbow Dislocation. WOUNDS: A Compendium of Clinical Research and Practice. 2018 Oct; 30(10): E93-E97. PMID: 30312970.
  1. Aalirezaie A, Anoushiravani A, Cashman J, Choon D, Danoff J, Dietz M, Gold P, Schwarzkopf R, Sheehan E, Vigante D. General Assembly, Prevention, Host Risk Mitigation - Local Factors: Proceedings of International Consensus on Orthopedic Infections. J Arthroplasty. 2018 Oct 18. doi: 10.1016/j.arth.2018.09.051. PMID: 30343966.
  1. Abouljoud MM, Backstein D, Battenberg A, Dietz M, et al. Hip and Knee Section, Treatment, Surgical Technique: Proceedings of International Consensus on Orthopedic Infections. J Arthroplasty. 2018 Oct 19 doi: 10.1016/j.arth.2018.09.029. PMID: 30348548.
  1. Dietz MJ, Bostian PA, Ernest EP, Klein AE, LaSala PR, Frye BM, Lindsey BA. Rate of Contaminated Operative Surfaces during Revision of Total Joint Arthroplasty. Arthroplasty Today. 2018 Oct 29;5(1):96-99. doi: 10.1016/j.artd.2018.09.007. eCollection 2019 Mar. PMID: 31020031.
  1. Kang J, Dietz MJ, Hughes K, Xing M, Li B. Silver Nanoparticles Present High Intracellular and Extracellular Killing Against Staphylococcus aureus. J Antimicrob Chemother. 2019 Jun 1; 74(6):1578-1585 doi: 10.1093/jac/dkz053. PMID: 30778552.
  1. FAITH-2 Investigators (Dietz M), Slobogean GP, Sprague S, Bzovsky S, Heels-Ansdell D, Thabane L, Scott T, Bhandari M. Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): Design and Rationale for a Pilot Multi-centre 2 × 2 Factorial Randomized Controlled Trial in Young Femoral Neck Fracture Patients. Pilot Feasibility Stud. 2019 May 28;5:70. doi: 10.1186/s40814-019-0458-x. eCollection 2019. PMID: 31161044.
  1. Dietz MJ, Klein AE, Lindsey BA, Duncan ST, Eicher JM, Gillig JD, Smith BR, Steele GD. Posterior Hip Precautions Do Not Impact Early Recovery in Total Hip Arthroplasty: A Multicenter, Randomized, Controlled Study. J Arthroplasty. 2019 Jul;34(7S):S221-S227.e1. doi: 10.1016/j.arth.2019.02.057. Epub 2019 Mar 13. PMID: 30975478.
  1. Kang J, Dietz MJ, Li B. Antimicrobial Peptide LL-37 is Bactericidal Against Staphylococcus aureus Biofilms. PLoS One. 2019 Jun 6;14(6):e0216676. doi: 10.1371/journal.pone.0216676. eCollection 2019. PMID: 31170191.
  1. Lastinger A, McLeod N, Dietz MJ, Guilfoose J, Sarwari AR. Clinical Experience with Tigecycline in the Treatment of Prosthetic Joint Infections. J Bone Jt Infect. 2019 May 21;4(3):126-132. doi: 10.7150/jbji.34866. eCollection 2019. PMID: 31192112.
  1. Dietz MJ, Moushmoush O, Samora WP, Kish VL, Hamlin BR. The Effect of Increasing Femoral Head Size on the Force Required for Dislocation. Surg Technol Int. 2019 Nov 10; 35. 426-429. PMID: 31282981.
  1. Bravin LN, Ernest EP, Dietz MJ, Frye BM. Liposomal Bupivicaine Offers No Benefit Over Ropivicaine for Multimodal Periarticular Injection in Total Knee Arthroplasty. Orthopedics. 2020 Mar 1;43(2):91-96. doi: 10.3928/01477447-20191223-01. PMID: 31881086 -- Editors Blue Ribbon Award.
  1. Dietz MJ, Ray JJ, Witten BG, Frye BM, Klein AE, Lindsey BA. Portable Compression Devices in Total Joint Arthroplasty; Poor Outpatient Compliance. Arthroplasty Today. 2020 Mar 6;6(1):118-122. https://doi.org/10.1016/j.artd.2019.12.004. PMID: 32211487.
  1. Parvizi J, Gehrke T, Krueger CA, Chisari E, Citak M, Van Onsem S, Walter WL; International Consensus Group (ICM; Dietz MJ) and Research Committee of the American Association of Hip and Knee Surgeons (AAHKS; Dietz MJ). Resuming Elective Orthopaedic Surgery During the COVID-19 Pandemic: Guidelines Developed by the International Consensus Group (ICM). J Bone Joint Surg Am. 2020 Jul 15; 102(14):1205-1212. doi: 10.2106/JBJS.20.00844. PMID: 32412924.
  1. Prince N, Penatzer, JA, Dietz, MJ, Boyd, JW. Impact of Cytokines and Phosphoproteins in Response to Chronic Joint Infection. Biology. 2020 Jul 16, 9(7), 167. https://doi.org/10.3390/biology9070167. PMID: 32708756.
  1. Prince N, Penatzer JA, Dietz MJ, Boyd JW. Localized Cytokine Responses to Total Knee Arthroplasty and Total Knee Revision Complications. J Transl Med. 2020 Aug 31;18(1):330. doi: 10.1186/s12967-020-02510-w. PMID: 32867801.
  1. Bostian PA, Ray JJ, Karolcik BA, Bramer MA, Wilson A, Dietz MJ. Thromboelastography is Predictive of Mortality, Blood Transfusions, and Blood Loss in Patients with Traumatic Pelvic Fractures: A Retrospective Cohort Study. Eur J Trauma Emerg Surg. Nov 11. doi: 10.1007/s00068-020-01533-8. PMID: 33175987.
  1. Prince N, Penatzer JA, Dietz MJ, Boyd JW. Tissue-level of Cytokines in a Rodent Model of Chronic Implant-Associated Infection. J Orthop Res. 2021 Oct; 39(10):2159-2168. doi: 10.1002/jor.24940. Epub 2020 Dec 15. PMID: 33283316.
  2. Brown TS, Bedard NA, Rojas EO, Anthony CA, Schwarzkopf R, Stambough JB, Nandi S, Prieto H, Parvizi J, Bini SA, Higuera CA, Piuzzi NS, Blankstein M, Wellman SS, Dietz MJ, Jennings JM, Dasa V; AAHKS Research Committee. A Brief Update on the Effect of the COVID-19 Pandemic on Hip and Knee Arthroplasty Patients in the United States. A Multicenter Update to a Previous Survey Study of Patients Postponed by the Pandemic. Arthroplasty Today. 2021 Feb;7:268-272. DOI: 10.1016/j.artd.2020.11.025. PMID: 33294537.
  1. Frye BM, Patton C, Kinney JA, Murphy TR, Klein AE, Dietz MJ. A Medial Congruent Polyethylene Offers Satisfactory Early Outcomes and Patient Satisfaction in Total Knee Arthroplasty. Arthroplasty Today. 2021 Jan 19;7:243-249.e0. doi: https://doi.org/10.1016/j.artd.2020.11.003. PMID: 33786348.
  1. Dietz MJ, Gilligan PH, Makani A, Machi AS. Flip Autograft Technique for Anterolateral Femoral Deficiency in Total Knee Arthroplasty. Arthroplasty Today. 2022 Apr 1; 15:29-33. doi: https://doi.org/10.1016/j.artd.2022.02.001. PMID: 35392364.
  1. Nandi S, Schwarzkopf R, Chen A, Seyler T, Wheeler L, Parvizi J, Dietz MJ, Brown TS, Clohisy JC, Courtney M, Levine BR, Mears SC, Otero JE, Sporer SM. Routine Pathologic Examination of Femoral Head Specimens from Total Hip Arthroplasty May Not Be Indicated or Cost-effective: A Systematic Review. Arthroplasty Today. 2022 May 9; 15:182-187; doi:https://doi.org/10.1016/j.artd.2022.03.016. PMID: 35774889.
  1. Dietz MJ, Moushmoush O, Frye BM, Lindsey BA, Murphy TR, Klein AE. Randomized Trial of Postoperative Venous Thromboembolism Prophylactic Compliance: Aspirin and Mobile Compression Pumps. J American Academy of Orthopaedic Surgeons. 2022 Oct 15;30(20):e1319-e1326. doi: 10.5435/JAAOS-D-21-01063. PMID: 36200820.
  1. Dietz MJ. Letter to the Editor: Editorial: Should Orthopaedic Residents Be Required to Do Research, or Would Critical Reading Programs Be a Better Use of Their Time? Clin Orthop Relat Res. 2022 Sep 1; 480(9):1841. doi: 10.1097/CORR.0000000000002285. Online ahead of print. PMID: 35767819.
  1. Bouji N, Wen S, Dietz, MJ. Intravenous Antibiotic Duration in the Treatment of Prosthetic Joint Infection: Systematic Review and Meta-analysis. Journal of Bone and Joint Infection, 2022 7(5); 191-202, https://doi.org/10.5194/jbji-7-191-2022. PMID: 36267262.
  1. Nandi S, Parvizi J, Adelani MA, Brown TS, Clohisy JC, Courtney PM, Dietz MJ, Levine BR, Mears SC, Otero JE, Schwarzkopf R, Seyler T, Sporer SM. Routine Pathologic Examination of Femoral Head in Total Hip Arthroplasty A Survey Study of the American Association of Hip and Knee Surgeons. Arthroplasty Today. 2023 Jan 14; 19:101079. doi: 10.1016/j.artd.2022.101079. eCollection 2023 Feb. PMID: 36691462.
  1. Pincavitch JD, Pisquiy JJ, Wen S, Bryan N, Ammons J, Makwana P, Dietz MJ. Thirty-Day Mortality and Complication Rates in Total Joint Arthroplasty After a Recent COVID-19 Diagnosis: A Retrospective Cohort in the National COVID Cohort Collaborative (N3C). J Bone Joint Surg Am. 2023 Jun 23;. doi: 10.2106/JBJS.22.01317. [Epub ahead of print] PubMed PMID: 37352338.
  1. Velayutham M, Poncelet M, Perini JA, Kupec JT, Dietz MJ, Driesschaert, Khramstov VV. EPR Viscometric Measurements Using a 13C-Labeled Triarylmethyl Radical in Protein-Based Biotherapeutics and Human Synovial Fluids. Appl Magn Reson 54, 779–791 (2023). https://doi.org/10.1007/s00723-023-01556-5
  1. Bostian PA, Vaida J, Brooks WC, Chaharbakshi E, Dietz MJ, Klein AE, Murphy TR, Frye BM, Lindsey BA. A Novel Protocol for Nasal Decolonization Using Prolonged Application of an Alcohol-Based Nasal Antiseptic Reduces Surgical Site Infection in Total Joint Arthroplasty Patients: A Retrospective Cohort.   Surgical Infections.  24, 7 (2023). doi: 10.1089/sur.2022.344. PMID 37638795
  1. Bravin LN, Dietz MJ. Biomaterials in Total Joint Arthroplasty. Orthopaedic Biomaterials – Progress in Biology, Manufacturing, and Industry Perspectives. New York; Springer, 2018: 175-199.

 

  1. Dietz MJ, Nazarian A. Chapter 44: The Valgus Knee: Considerations for Alignment and Balance. The Adult Knee. Philadelphia; Wolters Kluwer, May 2020.

 

  1. Vaida J, Dietz MJ. When the Race is Lost: The Clinical Impact of Prosthetic Joint Infections. Racing to the Surface: Advances in Antimicrobial and Osteoinductive Studies. New York; Springer, 2020: 3-31.